Human Male AB OTC Serum lacks antibodies against the A and B blood type antigens, which prevents reaction with cultured cells and is recommended for use in biomedical applications.
Human Male AB OTC serum is collected from whole blood and coagulates naturally after collection. Once clotted, the material is centrifuged to remove the clot and serum is separated, virally tested. The individual units are then pooled, filtered and bottled. Human Male AB OTC tends to have a slightly higher protein content than Human Male AB Serum and contains no anticoagulant. This material can be used for the same applications as Human Male AB Serum such as; tissue engineering, transplantation and expansion of T-cells, cell therapy applications and cell line testing for PBMCs, bone marrow, CD9, CD3 and CD33. Our Human Male AB OTC material is collected and processed using a closed loop system, in an ISO certified manufacturing facility under cGMP allowing the material to be used worldwide in clinical trials and for commercial use.
Human Male AB Serum is collected from the whole blood donation of healthy male AB donors at FDA-licensed centers within the US.
The whole blood is allowed to coagulate naturally after collection and once clotted, the material is centrifuged to remove the clot and serum is separated and virally tested. The individual units are then pooled, filtered and bottled.
- Each Individual unit is tested and found negative for all required viral markers using FDA-approved methods
- Testing at CLIA certified labs
- HIV-1, HCV and HBV by Nucleic Acid Test, WNV and Zika by Nucleic Acid Test, Anti-HIV 1 / 2, Anti HCV, HBsAg, Chagas & Syphilis
- Additional testing provided by Access: Anti HBC, Mycoplasma, Endotoxin, USP Sterility, Hemoglobin, Osmolality, pH, Chemistry, and Species Testing
- Additional testing available upon request
- .1µm sterile-filtered
- Higher protein content than standard plasma
- Custom donor pools available
- Heat Inactivation and gamma irradiation available upon request
- Gamma irradiation is through a validated process
- Virus validation study completed March 2019
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